Dr. S. L. Dasari had submitted his dissertation
in 2006 Year, for the
P.G. degree M. Phil. in Ayurveda. His guide was Dr.
T. M. Nesari & research center was
Tilak Ayurved Mahavidyalaya, Pune (M.S.) India ,
& submitted to University
of Pune
Dr. Dasari had done randomized
single blind controlled clinical trials on 60 geriatric patients to assess
Rasayana and anti-aging effects of vruddhadaru (Argyreia nervosa).
500
mg tablets of root powder of vruddhadaru were prepared and were given to 30
patients of group A in a dose of 6 tablets BID for the duration of 2 month. 30 patients of
placebo group B was received starch tablets in the same manner as in A.
Criteria
of assessment was-
i)
Gradation from 1 to 3 was given for each effect of
general feeling of well being & improvement in the quality of life as per
CRF.
ii)
Improvement in gradation of signs & symptoms of
aging (as per NIA).
iii)
DHEA-S estimation.
iv)
Fat percentage.
v)
PFV.
vi)
Haemogram.
vii)
Weight.
The research work was
concluded as follows-
Vruddhadaru
(Argyreia nervosa) showed good anti-aging (Vayasthapana) activity in
Geriatric persons when given in the dose of 6 tab BD for 2 months ( Each tab
contains 500 mg of root powder )
1) Argyrea speciosa
exerted a good enhancing effect on DHEA-S.
2)
Argyrea speciosa significantly increased appetite in
older age group.
3)
A. speciosa induced a note worthy change in well
being of patients, and symptom of aging tiredness was improved.
4)
A. speciosa did not helped in memory in induced by
aging in two months.
5)
There was no change in vision & hearing loss in
old age.
6)
There was no change seen in hair colour & hair
loss.
7)
The drug brought significant change in urinary
complaints in males & females but there was no change in behavior of aged
persons & in skin elasticity.
8)
The drug exerted good significant change in
regulation of bowels.
9)
The drug showed enhancement in fat % & weight
& significant reduction in ESR & PCV was improved.
10) There was no change in
Hb% & in total leucocytes count
In short Vruddhadaru shoed good anti-aging (Vayasthapana)
activity in Geriatric persons.
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