Friday 20 February 2015

:- Selection of Ayurvedic anti-malarial plants, Design of an anti malarial formulation and clinical evaluation.


 Title:- Selection of Ayurvedic anti-malarial plants, Design of an anti malarial formulation and clinical evaluation. 

Dr. N. B. Ghiware had submitted her dissertation in 2000 Year, for the P.G. degree M. Phil. Ayurved. Her guide was Dr. J.  K. Barde & research center was Tilak Ayurved Mahavidyalaya, Pune (M.S.) India, & submitted to University of Pune. 

Dr. Ghiware had done clinical study on two plants viz. Piper nigrum (maricha) & Nictanthus arbortoitis (Parijatak) to assess their efficacy against malaria. 

30-40 patients were selected who showed positive smear for P. vivax, P. ovale or P. malariae and the symptoms associated with Headache, Body ache, Chills, Anemia, fever & nausea or vomiting like symptoms.  

Tablets were prepared from 250 mg dried unripe fruits of maricha & 250 mg dried leaves of parijataka and given in a dose of 2 tablets twice a day with gap of 12 hrs for, 15 days.

Record of improvement in signs & symptoms was maintained after 1st & 2nd week of treatment & data was prepared. Effectiveness of treatment was judged only on reduction in signs & symptoms in malaria. 

The research work was concluded as follows- 

When Parijatak & Black pepper tablet was given 2 BD for 15 days ,it showed marked improvement in the patients of Malaria 

1)    After one week it is observed that condition of malarial patients was improved.

2)    After 15 days marked improvement was observed in the important signs & symptoms of malaria.

3)    Any direct effect on malarial parasite was not the part of studies.

 

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